Exploring Processes C and S Part 1: Napping Protocol
Learn how sleep researchers use a "napping" protocol to separate effects of processes C and S on sleep
The Suprachiasmatic Nucleus: Lesion & Transplant Experiments
Learn about landmark experiments that demonstrated the role of the suprachiasmatic nucleus (SCN) in circadian rhythms
Exploring Processes C and S Part 2: Forced Desynchrony
Learn how sleep researchers use a "forced desynchrony" protocol to separate effects of processes C and S on sleep
Human Circadian Variation: Genetic Approaches
Learn how genetic manipulations in model organisms and in vitro establish circadian links to human variation in chronotype
Fluence Response Curves and Action Spectra Series
Discover how action spectra are derived from fluence response curves
Photoperiodic Flowering Part 2
Part 2, the advanced mechanisms how plants measure night- and day-length to determine when to flower
Entrainment Simulator
Explore basic concepts of circadian entrainment, phase response curves, and phase shifts with our Entrainment Simulator
Luciferase Reporters in Circadian Research
Learn how luciferase reporters are used in circadian biology
Common Clock Mechanism Graphics Tool
Use our free editable powerpoint file of mammalian, fly, and plant molecular clock mechanisms in presentations and papers
Mammalian Molecular Entrainment to Light and Networks
Learn how light information alters the molecular circadian clock to promote entrainment
Establishing the Genetic Basis of Circadian Rhythms: A Landmark Study
Learn about basic property of free-running periods of circadian oscillators
Bioluminescent and Fluorescent Reporters in Circadian Rhythm Studies
Read about the biology, application, and experimental design of fluorescent reporters in circadian studies
Links Between Mood Disorders and Circadian Rhythms
Learn about the behavioral assays and gene manipulations used in rodent models to explore links between circadian rhythms and mood disorders
Interview with Dr. Carrie Partch
Hear Dr. Partch discuss the structural underpinnings of molecular clocks
In-Lab Video Series: Rodent Wheel-Running Experiment
Learn how to design, perform, and analyze a rodent wheel-running experiment.
An Introduction to Chronobiology
Read our three-part introduction to basic concepts in chronobiology
Cyanobacterial Circadian Clock Output Mechanism
Discover how the core circadian oscillator in the cyanobacterium Synechococcus elongatus sends output to regulate timing
The 2-Process Model of Sleep
Learn how a homeostatic drive and the circadian clock control the timing of sleep
Properties of Entrainable Oscillators
Learn the properties that define an entrainable biological circadian oscillator
Cellular Oscillators
Learn about "clocks in a dish," and how in vitro mammalian clocks can be used to study circadian rhythms