The BioClock Studio Proudly Presents…

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Circadian Fundamentals
Advanced Circadian Biology |
MODELS: Mammals
Photosynthetic Processes
Invertebrates
Humans |
TOPIC: Historical
Light
Metabolism
Cellular Mechanisms
Sleep
Techniques
Interactive Tutorials
Interviews
Readings

Entrainment Simulator

Explore basic concepts of circadian entrainment, phase response curves, and phase shifts with our Entrainment Simulator

Interview with Dr. Carrie Partch

Hear Dr. Partch discuss the structural underpinnings of molecular clocks

Bioluminescent and Fluorescent Reporters in Circadian Rhythm Studies

Read about the biology, application, and experimental design of fluorescent reporters in circadian studies

The 2-Process Model of Sleep

Learn how a homeostatic drive and the circadian clock control the timing of sleep

Time Memory in Bees

Learn about landmark experiments that established internal clocks as the source of circadian rhythms in animals

Shift Work, Sleep Deprivation, and Health

Discover the health impacts of shift work and sleep deprivation on humans

Establishing the Genetic Basis of Circadian Rhythms: A Landmark Study

Learn about basic property of free-running periods of circadian oscillators

Human Circadian Variation: Genetic Approaches

Learn how genetic manipulations in model organisms and in vitro establish circadian links to human variation in chronotype

Circadian Transcriptomics Dry Lab Series

Learn the approaches and experimental design of circadian -omics studies in a “dry lab” format

School Start Time Infographic

Learn why school start times matter for adolescents

Phase Response Curves

Understand phase response curves, an important - but tricky! - circadian concept

Photoperiodic Flowering Part 2

Part 2, the advanced mechanisms how plants measure night- and day-length to determine when to flower

The Food Entrainable Oscillator

Learn about the discovery and characteristics of the non-canonical Food Entrainable Oscillator

Effects of Sleep Deprivation on Attention and Mood

Learn about the effects of sleep deprivation on attention and mood.

Exploring Processes C and S Part 2: Forced Desynchrony

Learn how sleep researchers use a "forced desynchrony" protocol to separate effects of processes C and S on sleep

Healthy Light Exposure Infographic

Learn the do's and don'ts of light exposure that affect circadian rhythms and sleep

Structural Changes of the Cyanobacterial Clock

Watch the structural nanomachine of the cyanobacterial circadian oscillator come to life in this video made by our colleagues.

Interview with Dr. Lance Kriegsfeld

Hear Dr. Kriegsfeld discuss circadian rhythms and neuroendocrinology

Photoperiodic Flowering Part 1

Discover how plants measure night- and day-length to determine when to flower

Mammalian Retina and Photoreceptors

Understand the biology behind photoreception in mammals

Circadian Clock-Controlled Genes Part 1

An introductory tutorial video on the mechanisms of mammalian molecular circadian clock regulation, and how the clock regulates other genes.

Luciferase Reporters for Cyanobacteria in Circadian Research

Learn how luciferase reporters are used to study circadian rhythms in cyanobacteria

Mammalian Molecular Entrainment to Light and Networks

Learn how light information alters the molecular circadian clock to promote entrainment

Avian Photoreception

Virtually perform landmark experiments in avian circadian photoreception with our "Ex-Sparrow-ment" Simulator

Circadian Clock-Controlled Genes Part 2

The second part tutorial on the mechanisms of mammalian molecular circadian clock regulation, and how the clock regulates other genes.

Cellular Oscillators

Learn about "clocks in a dish," and how in vitro mammalian clocks can be used to study circadian rhythms

Free-Running Periods