Circadian biologists have a specialized toolbox of experimental techniques and approaches, many of which are discussed within each tutorial. The videos in this section focus on the techniques.

Bioluminescence & Luciferase Reporters

Read our overview of bioluminescence and luciferase reporters, which are used for a variety of applications in biological research.

This tutorial provides a visual explanation of luciferase reporters and how they are used throughout biology.

The following videos discuss the the application of luciferase reporters for circadian biology in cyanobacteria and mammals:

Many of these approaches rely on “cell culture”, the technique of keeping cells (and their oscillators!) alive in a dish. This tutorial offers an overview of mammalian cell culture in circadian biology.

In whole animals, the ability to detect changes in gene expression at multiple time- or treatment points allowed transcriptomics to greatly enhance our understanding of circadian biology; view our “Dry Lab” series to understand how circadian transcriptomics studies are performed, analyzed, and visualized.

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